At The Compounding Lab we compound many preparations that support and assist in creating wellness in Fibromyalgia. The area we have made the greatest improvement has been Transdermal Pain Creams that are discussed in that section and the compounding of Low Dose Naltrexone Capsules.
Low Dose Naltrexone:
Low Dose Naltrexone (LDN) is an exciting treatment option for multiple sclerosis, HIV/AIDS, cancer, central nervous system disorders, and other conditions in which patients benefit from the immune system enhancing effects of LDN. As the most reliable source for low dose naltrexone in Brisbane, as we follow the most stringent standards of potency testing for all compounded pharmaceuticals.
The commonly available form of Naltrexone comes in 50 mg, the dosage appropriate for blocking the effects of opiate based drugs, which is the FDA approved purpose. Low dose naltrexone has been found to be effective in boosting immune system functioning in doses of 1.5 to 4.5 mg, but we dont have a commercially available form at these strengths approved by the TGA. There is a substantial and growing body of scientific evidence to support the use of low dose naltrexone, as well as thousands of individuals who have benefited from its use for a variety of conditions.
How low dose Naltexone Works has many therories in essence it reduces cell division and binds to Opioid Growth Factors. Cell division - All agree that normal regulation of the division of cells is a good thing. When cell division gets out of control we call it cancer and several other names. That’s when doctors and patients want a method to return the cell division to normal.
Opioid Growth Factor - Produced naturally, an endorphin called OGF or Opioid Growth Factor keeps cell growth in control. An endorphin is a naturally occurring chemical in your body. OGF is an endorphin that’s produced by every cell in the body. OGF binds to a special receptor known as Opiod Growth Factor Receptor - OGFR or Opioid Growth Factor Receptor. OGFR is present on the surface of every type of cell. When OGFR binds to and OGF Receptor a cascade of events occurs that helps to control cell growth. It’s vital that OGF is first produced by the cells and that it then binds to the OGF Receptor. If it’s not produced or it does not bind to the receptors your body won’t work as it’s supposed to. OGF produced in blood cells that control the immune system regulates the growth of these cells and keeps the immune system balanced and functioning properly.
Naltrexone effects on the OGF - When Naltrexone binds to an OGF Receptor it blocks the receptor preventing OGF from binding there. Resulting in the affected cells becoming deficient in OGF.
Three Processes occur:
1.More OGF Receptors
2.Receptors More Sensitive
3.More OGF Produced
BIG differences between Naltrexone and using Low dose Naltrexone (LDN)
1.Administering a low dose of Naltrexone blocks the OGF Receptor for only a few hours
2.Only a low dose of Naltrexone will be metabolized fast enough so low side effects seen