There are many important metabolites produced by Escherichia coli strain Nissle 1917, this and together with all its characteristics makes this strain one of the most important for overall gut health.
As one of the first colonizers of the infant gut, Escherichia coli strain Nissle 1917 plays a vital role in the establishment and maintenance of a healthy gut and provides microbial barrier against pathogenic bacteria.
Its metabolic activities, consumption of oxygen, production of short chain fatty acids (SCFA) helps create an environment in which subsequent anaerobic microorganism can establish and so begins this complex Gut Microbiome which plays a crucial role in our health.
Escherichia coli is responsible for the production of a number of important metabolites.
Escherichia coli produces – Chorismate
Chorismate is the precursor to the production of:
menaquinone (Vit K2)
Escherichia coli strain Nissle 1917 has shown to effect the immune system by influencing the maturation and development of the gut-associated lymphoid tissue (GALT) and can regulate the production of some immune mediators.
When there is a change in the composition of our gut microbiota there will also be a change in the metabolites produced and these in turn will place stress on the bacterial community. This change or altered bacterial composition is often referred to as Dysbiosis.
Mutaflor® should be stored in the refrigerator at (2-8°C). A short break in refrigeration at room temperature (up to 72 hours or 3 days) will not harm the product. Delivery of Mutaflor® to Australia follows strict ‘Cold Chain’ processes. The specially designed pallet thermobox enables Mutaflor® to be air-freighted and temperature data logging confirms this process. Distribution within Australia is via ice filled foam cartons and is for most locations an overnight delivery. Mutaflor® does not contain lactose, gluten or wheat.